anodal tDCS through the left dorsolateral prefrontal cortex (DLPFC) can enhance neural connectivity in the fronto-parietal networks and can increase intelligence in individuals with autism. Therefore, this study aimed to investigate the effect of anodal tDCS on IQ changes in high function autism spectrum disorder patients. Autism spectrum disorder
Conditions
Interventions
Two main outcomes were assessed in this study, the primary outcome was the ATEC social subscale, and the secondary outcome was the IQ. We also assessed vital signs, physical examination, and neurologi
Experimental Device
IQ test
Sponsors
Khon Kaen University
Faculty of Medicine, Khon Kaen University
Eligibility
Sex/Gender
All
Age
15 Years to 30 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were as follows: (a) mild to moderate autistic symptoms (Childhood Autism Rating Scale, CARS score 30-36.5) where the patient can co-operate in IQ examination; (b) aged between 15 and 30 years; (c) normal brain structure evaluated by MRI; and (d) the caregiver together with the patients consented to participate in the research.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: (a) severe neurological disorders such as brain tumor, intracranial infection, and uncontrollable epilepsy; (b) uncooperative parents; and (c) received other new treatments during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IQ level 2 time points, at baseline and 2 weeks post treatment Test of Nonverbal Intelligence, fourth edition (TONI-IV) | — |
Secondary
| Measure | Time frame |
|---|---|
| ATEC score 2 time points, at baseline and 2 weeks post treatment Autism Treatment Evaluation Checklist | — |
Countries
Thailand
Contacts
Public ContactParadee Auvichayapat
Khon Kaen University
Outcome results
None listed