Healthy condition Zuper rice Color rice Anti-ageing Physical and psychological wellness Age-related disorders
Conditions
Interventions
Subjects received the placebo product which has the same color and smell and looks like Zuper rice capsules.,Subjects received capsules containing Zuper rice 2 g per day.,Subjects received capsules co
Placebo,Zuper rice capsules 2 g/day,Zuper rice capsules 4 g/day
Sponsors
Program Management Unit Competitiveness (PMUC)
CHIA MENG MARKETING COMPANY LIMITED
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 45-65 years old 2.Body Mass Index (BMI) 18-25 kg/m2 3.DASS-21 score less than 7 4. Do not consumption of probiotic foods such as Yakult, fermented milk, and yogurt on a regular basis
Exclusion criteria
Exclusion criteria: 1. Volunteers who have been diagnosed with one of the following; cardiovascular diseases, lung disease, allergies, thyroid disease, adrenal gland, pituitary gland, diabetes mellitus, cancer, liver disease, kidney disease, and head injury 2. Volunteers who use drugs that affect blood glucose levels, lipid-lowering, antihypertensives, or nonsteroid anti-inflammatory drugs 3. Volunteers who require supplements or any drug that effect on the nervous system or cardiovascular or metabolism and weight loss before the start of the test. 4. Volunteers who use contraceptive pills, hormones, or any supplements 5. Drinking alcohol more than 5 times/day 6. Smoking more than 10 pieces/day 7. Volunteers who have regular exercise more than 3 times/week 8. Volunteers who participate in other projects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Telomere length 12 weeks qRT-PCR method | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of Inflammatory markers; PPAR, NF-kB, TNF alpha, and IL-6 12 weeks ELISA method,Evaluation of Nitric oxide (NO), Endothelin, Prostacyclin, ACE, AIP, VCAM1, ICAM1, and Selectin level 12 weeks ELISA method,Evaluation of Oxidative stress markers; MDA, SOD, CAT, GSH-Px, and 8-OHDG 12 weeks ELISA method,Evaluation of Homocysteine and BDNF level 12 weeks ELISA method,Evaluation of Metabolic profiles; Insulin, HbA1C, and HOMA-IR 12 weeks laboratory,Evaluation of Vitamin B6, B9, B12, GABA and Total anthocyanin level 12 weeks laboratory,Evaluation of Skin ageing; Hydration, Wrinkle and Elasticity 12 weeks observation,Evaluation of Endothelial function and Endothelial vascular ageing 12 weeks equipment,The changes of Computerized battery test 12 weeks equipment,The changes of Electrocardiogram 12 weeks Electrocardiography,Stool examination; PH, Lactobacillus spp., and Bifidobacterium spp. 12 weeks laboratory,Evaluation of Physical and Psychological fitness 12 weeks equipment and questionnaire,The changes of hematological and clinical chemistry parameters 12 weeks laboratory | — |
Countries
Thailand
Contacts
Public ContactJintanaporn Wattanathorn
Faculty of Medicine, Khon Kaen University
Outcome results
None listed