chronic polycystic ovarian syndrome chronic polycystic ovarian syndrome
Conditions
Interventions
The pharmacist was instructed to give the drug for three months at a predetermined dose every day (metformin 2x500 mg). ,The pharmacist was instructed to give the drug for three months at a predetermi
Active Comparator Drug,Active Comparator Drug,Active Comparator Drug
Metformin,DLBS 3233,Vaccinium myrtillus extract
Sponsors
Local, in Arifin Achmad Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 44 Years
Inclusion criteria
Inclusion criteria: All patients who satisfied the Rotterdam PCOS criteria for chronic polycystic ovarian syndrome, which includes oligomenorrhea or amenorrhea and at least one of the two symptoms of hyperandrogenism (clinical or biochemical proof of it) or polycystic ovaries on ultrasound, ready to take part in research and willing to follow research protocol, and HOMA-IR > 2.0.
Exclusion criteria
Exclusion criteria: (1) People with comorbid conditions; (2). Treatment for insulin sensitivity within three months before the study or during the study; (3) Drug hypersensitivity reactions that are well-known; and (4) A body mass index that is less than 20 or higher than 50 kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rotterdam criteria and HOMA-IR Three months Direct assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of pregnancy and the treatment side effects Three months Interview,Improvement of the BMI, upper arm circumference, abdominal circumference and endometrial thickness Three months Direct assessment | — |
Countries
Indonesia
Contacts
Public ContactImelda Hutagaol
Faculty of Medicine, Universitas Riau
Outcome results
None listed