The Effect of Topical Sucralfate on Symptomatic Relieved of Hemorrhoid and Anal Fissure, A Case Series

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20221013003

Enrollment

Registered

2022-10-13

Start date

2022-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolapsed internal hemorrhoid Anal fissure anal fissure, prolapsed hemorrhoid, internal hemorrhoid, sucralfate, quality of life

Interventions

Sucralfate rectal suppository hs for 10 days Sucralfate ointment apply hs for 14 days

Experimental Drug

Topical sucralfate

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Prolapsed internal hemorrhoid (grade 1-3) 2. Symptomatic subacute and chronic anal fissure

Exclusion criteria

Exclusion criteria: 1. Bleeding hemorrhoid 2. External hemorrhoid 3. Acute anal fissure 4. Pregnant or breastfeeding women 5. Allergy to lanolin, coco, sucralfate, calendula, chamomile, witch hazel

Design outcomes

Primary

Measure	Time frame
Symptomatic relieved and quality of life improvement 14 days after intervention HemoFiss score	—

Secondary

Measure	Time frame
Healing of anal fissure 14 days after intervention Rectal examination by proctoscopy	—

Countries

Thailand

Contacts

Public ContactAitsariya Mongkonsupphawan

General surgery department, Siriraj hospital

Aitsariya.mon@mahidol.ac.th0863628562

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026