Respiratory Drive and Survival in Comatose Out-of-Hospital Post Cardiac Arrest Patients

Alteration of respiratory drive in comatose out-of-hospital post cardiac arrest patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20221010003

Enrollment

Registered

2022-10-10

Start date

2022-10-28

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Out-of-hospital cardiac arrest adult patients post cardiac arrest

Interventions

Comatose out-of-hospital cardiac arrest patients

Diagnostic

Out-of-hospital cardiac arrest patients

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age more than or equal 18 years 2. Out of hospital cardiac arrest 3. Sustained Return of spontaneous circulation (ROSC) - defined as 20 minutes with signs of circulation without the need for chest compressions. 4. Unconsciousness defined GCS < 8 5. Admitted in the medical intensive care unit or cardiac care unit within 24 h after ROSC 6. On ventilator with P0.1 available

Exclusion criteria

Exclusion criteria: 1. On Extracorporeal Membrane Oxygenation 2. Obvious or suspected pregnancy 3. Intracranial bleeding 4. Severe chronic obstructive pulmonary disorder (COPD)

Design outcomes

Primary

Measure	Time frame
The airway occlusion pressure (P0.1) 24, 48 and 72 h after hospital admission P0.1 maneuver on ventilator,Survival At discharge Survival to hospital discharge	—

Secondary

Measure	Time frame
Respiratory parameters 24, 48 and 72 h after hospital admission tidal volume, minute ventilation, respiratory rate ,Arterial blood gas 24, 48 and 72 h after hospital admission pH, pCO2, PO2,Neurological outcome At hospital discharge Cerebral performance catagories	—

Countries

Thailand

Contacts

Public ContactVeerapong Vattanavanit

Faculty of Medicine, Prince of Songkla University

vveerapong@gmail.com0848456228

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026