Pulmonary Hypertension Acyanotic Heart Disease Pulmonary Hypertension Acyanotic Heart DIsease Pomegranate
Conditions
Interventions
Lactose was given as placebo.,Pomegranate extract was given with dosage 120 mg per one kg body weight
Placebo Comparator Drug,Experimental Dietary Supplement
Control,Pomegranate Extract
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
1 Months to 10 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria are patient age 1 month until 10 years, diagnosed with acyanotic heart disease left to right shunt, given standard lung hypertension treatment and the parent had signed informed consent.
Exclusion criteria
Exclusion criteria: Subjects were excluded if they had prior heart surgery, were planned to have surgery within 3 months, had chronic parenchymal lung disease, had chromosomal or other disease preventing normal development, had infection or renal impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary Arterial Pressure 3 months Echocardiography | — |
Secondary
| Measure | Time frame |
|---|---|
| NT pro BNP and ADMA 3 months Laboratory,Functional Pulmonary Arterial Pressure 3 months PVRI Pediatric functional classification | — |
Countries
Indonesia
Contacts
Public ContactMahrus Rachman
Universitas Airlangga
Outcome results
None listed