Effect of a single-dose Dexmedetomidine on postoperative delirium and intraoperative hemodynamic outcomes in elderly hip surgery; A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20221004001

Enrollment

200

Registered

2022-10-04

Start date

2022-10-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The incidence of postoperative delirium in elderly hip surgery is high Hip fractures, delirium, frail elderly

Interventions

Dexmedetomidine intravenous 0.3-0.4 mcg/kg before surgical started diluted in syringe total 10 cc,Normal saline in syringe 10 cc

Experimental Drug,Placebo Comparator No treatment

Dexmedetomidine,Normal saline

Eligibility

Sex/Gender

All

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. aged >/= 65 years 2. Hip fracture undergoing surgery 3. Anesthetic technique: regional anesthesia and pain controlled with peripheral nerve block+ IV opioid

Exclusion criteria

Exclusion criteria: 1. Allergy or contraindication to dexmedetomidine 2. Preoperative delirium 3. Underlying disease: neurovascular disease, e.g., stroke 4. Underlying disease: Phycosis 5. Anesthetic technique: general anesthesia

Design outcomes

Primary

Measure	Time frame
Incidence of Postoperative delirium at PACU, 24 hrs, , 48 hrs. and 72 hrs. 3D-CAM	—

Secondary

Measure	Time frame
Intraoperative hemodynamic outcomes intraoperative periods Heart rate, blood pressure, sedation score	—

Countries

Thailand

Contacts

Public ContactChidchanok Choovongkomol

Maharat Nakhonratchasima hospital

thisismemoen@gmail.com044235040

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026