Patients who have moderate bilateral facial inflammatory acne inflammatory acne, acne vulgaris, laser, dual wavelength laser
Conditions
Interventions
Each patient was randomized to receive 589/1319 nm laser treatment on either the left or the right side of the face. Patients underwent four treatment sessions at 2-week intervals (at week 0, week 2,
Solid-state Dual Wavelength 589 and 1,319 nm Laser and 2.5% Benzoyl peroxide,2.5% Benzoyl peroxide
Sponsors
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Healthy males and females between 18 to 50 years old 2. Patients who have moderate bilateral facial inflammatory acne with the presence of at least five acne papules or pustules per each side of the face 3. Fitzpatrick skin Types III to V 4. Patients willing to follow up and comply with the study protocol who appreciates to participate in this study by signing the consent form
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating woman 2. Patients who had received oral vitamin A derivatives in the past 3 months 3. Patients who had received any other systemic or topical acne therapies, alpha hydroxy acid or glycolic acid, beta hydroxy acid or salicylic acid within 1 month 4. Patients who had received oral contraceptives for within 3 months 5. Patients receiving facial laser treatments within the past 3 months 6. Patients with history of photosensitive disease 7. Patients with any medical condition that might affect acne and wound healing process 8. Patients who withdrew from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory acne lesion count at baseline, week 2, week 4, week 6, week 10, week 14 and week 18 The number counted | — |
Secondary
| Measure | Time frame |
|---|---|
| Facial acne severity at baseline, week 2, week 4, week 6, week 10, week 14 and week 18 Investigator's Global Assessment (IGA) of acne severity,Improvement of facial post-acne erythema at baseline, week 2, week 4, week 6, week 10, week 14 and week 18 Antera 3D skin analysis camera ,Improvement of facial acne scar and/or skin texture at baseline, week 6, week 10, week 14 and week 18 Antera 3D skin analysis camera,Pain score assessment at week 0, week 2, week 4 and week 6 Visual analogue scale from 0 to 10 ,Patient satisfaction score at week 6, week 10, week 14 and week 18 Visual analogue scale from 0 to 10,Safety every visit side effects | — |
Countries
Thailand
Contacts
Public ContactPenpun Wattanakrai
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital
Outcome results
None listed