Patient with impacted mandibular third molar on both sides of mouth. Oral magnesium Magnesium supplement Analgesic adjuvant coanalgesic Postoperative pain Wisdom tooth Third molar
Conditions
Interventions
Magnesium 500 mg/tablet which the participants will take a tablet orally immediately prior to surgery. They will continue to take for 3 days postoperatively in the same amount and at the same time as
Experimental Dietary Supplement,Placebo Comparator No treatment
Oral magnesium 500 mg,Placebo Group
Sponsors
Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years old. 2. Healthy status (American Society of Anesthesiologists (ASA) Class I and II). 3. Required removal of both impacted mandibular third molar. 4. Needed bone removal and/or tooth sectioning for removal of the mandibular third molars.
Exclusion criteria
Exclusion criteria: 1. History of allergy to medications used in this study. 2. Pregnancy or breast feeding. 3. History of systemic disease or conditions contraindicated to magnesium. 4. Presence of ongoing pain originated from mandibular third molar or orofacial region on the day of surgery. 5. History of analgesic intake within 1 week prior to surgery. 6. History of medication or supplement intake that can affect body magnesium level. 7. Psychiatric disorder. 8. Being unable to record postoperative outcomes and attend follow-up appointments. 9. Presence of signs and symptoms of local and/or systemic infection or associated pathology. 10. Removal of more than one third molar at the same sitting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity at rest 6, 24, 48, and 72 hours after third molar surgery Heft-Parker visual analog scale,Postoperative pain intensity on jaw movement 6, 24, 48, and 72 hours after third molar surgery Heft-Parker visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of analgesic consumptions after surgery at specific time 1 week after surgery Patient reported outcome using a questionnaire and pill count,Composite of adverse events from magnesium intake 1 week after surgery Patient reported outcome using a questionnaire | — |
Countries
Thailand
Contacts
Public ContactWarit Powcharoen
Chiang Mai University
Outcome results
None listed