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Prone position in COVID-19 patients effect peripapillary retinal nerve fiber layer thickness and ganglion cell layer thickness

The prone position for COVID-19 cases impacts the thickness of peripapillary retinal nerve fiber layers and ganglion cell layers: a prospective longitudinal study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20220930001
Enrollment
75
Registered
2022-09-30
Start date
2021-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recovery Covid-19 patients who recieved Prone position Covid-19 Prone position

Interventions

Covid-19 patient with Prone position,Covid-19 patient without Prone position,healthy age-sex match control
Other,Other,Other
Prone,Non-Prone,control

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. first COVID-19 diagnosis confirmed by a positive RT-PCR test via nasopharyngeal swab 2. recovered from COVID-19 (2-4 weeks following negative RT-PCR) 3. tested at Siriraj Hospital during 1 September 2021 to 1 January 2022.

Exclusion criteria

Exclusion criteria: 1. ophthalmic condition influencing p-RNFL and m-GCIPL thickness: abnormalities of the congenital optic nerve head, glaucoma, macular disease, uveitis, retinal vascular disorders, myopia with refractive error exceeding 4 diopters, previous intraocular surgery, cataracts, intraocular pressure more than 21 mmHg 2. neurological or systemic conditions influencing p-RNFL and m-GCIPL thickness, such as Alzheimer, diabetes mellitus, Parkinson, or multiple sclerosis 3. clinical status instabilities which presented difficulties in the investigation 4. patients unable to cooperate or remain seated for long periods

Design outcomes

Primary

MeasureTime frame
peripapillary retinal nerve fiber layer thickness at 1,3,and 6 month after recovery Cirrus OCT

Secondary

MeasureTime frame
ganglion cell layer thickness at 1,3,and 6 month after recovery Cirrus OCT

Countries

Thailand

Contacts

Public ContactNiphon Chirapapaisan

Faculty of Medicine Siriraj Hospital, Mahidol University

niphon.chi@mahidol.ac.th0896685735

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026