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Incidence of glaucoma conversion in patients with large cup to disc ratio

Incidence of glaucoma conversion in patients with large cup to disc ratio

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20220928004
Enrollment
340
Registered
2022-09-28
Start date
2022-10-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with large cup to disc ratio (more than or equal to 0.5) glaucoma suspected glaucoma conversion large cup to disc ratio enlarge cupping

Interventions

patients with large cup to disc ratio (more than or equal to 0.5) without any evidences of glaucoma including glaucomatous visual field defect or IOP more than 21 mmHg or abnormal OCT result which can
Diagnostic
patients with large cup to disc ratio (more than or equal to 0.5)

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with a cup to disc ratio more than or equal to 0.5 (reported from OCT result) from Faculty of Medicine, SIriraj hospital during 2008 - 2021 2. Intraocular pressure does not exceed 21 mmHg by regular inspection (at least 3 times per year) 3. No glaucomatous visual field defect reported by Humphrey visual field 4. Patients have at least 1 fundus photography 5. Patients have at least 1 optical coherence tomography

Exclusion criteria

Exclusion criteria: 1. Patients who have other ophthalmologic conditions that affect optic disc, cornea, retina, visual field, and intraocular pressure (except cataract) 2. Patients who receive intraocular surgeries or interventions which affect intraocular pressure before enrolling in this study 3. Patients who can not cooperate with Humphrey visual field test 4. Patients who do not have adequate information from the medical record (requires at least three years consecutively)

Design outcomes

Primary

MeasureTime frame
Glaucoma conversion rate any time after enrolling the patients incidence rate

Secondary

MeasureTime frame
Risk factors for developing glaucoma any time after enrolling the patients Kaplan-Meier Graph with Hazard ratio

Countries

Thailand

Contacts

Public ContactNaris Kitnarong

Faculty of Medicine Siriraj Hospital, Mahidol University

kitnarong.n@gmail.com0818080001

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026