Visual outcomes of hyperbaric oxygen therapy in acute central retinal artery occlusion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20220920004

Enrollment

Registered

2022-09-20

Start date

2021-02-17

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central retinal artery occlusion (CRAO) is an emergency ophthalmic event that has pathophysiology similar to acute cerebral ischemia. It is a rare condition, which incidence is approximately 1-2 in 100,000 people but has subsequent devastating visual outcomes. Visual acuity deteriorates to 20/400 or worse in most patients. CRAO, Central Retinal Artery Occlusion, Hyperbaric Oxygen Therapy

Interventions

CRAO patient receiving Hyperbaric oxygen therapy and conventional treatments,CRAO patient receiving only conventional treatments but not hyperbaric oxygen therapy

Treatment,Treatment

HBOT group,non-HBOT group

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who were at least 18 years of age and had onset of CRAO within 24 hours

Exclusion criteria

Exclusion criteria: Patients who received recombinant tissue plasminogen activator or had complications affecting visual acuity from conventional treatment of CRAO.

Design outcomes

Primary

Measure	Time frame
Improvement of Visual acuity date of discharge logMAR	—

Secondary

Measure	Time frame
Visual acuity date of discharge logMAR,Visual acuity 1 month after onset logMAR	—

Countries

Thailand

Contacts

Public ContactSomanus Thoongsuwan

Faculty of Medicine Siriraj Hospital, Mahidol University.

somanus@hotmail.com66818540693

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026