Gastroesophageal reflux disease FODMAPs, GERD, Gastric emptying, Gastric accommodation
Conditions
Interventions
High FODMAPs food which nutrition component and ingradient controlled ,Low FODMAPs diet which nutrition component and ingradient controlled
High FODMAPs diet,Low FODMAPs diet
Sponsors
Faculty of Medicine, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis Gastroesophageal reflux disease by symptom for within 3 months 2. Age 18-70 yr 3. Underwent the EGD within 6 months 4. Have a symptom of GERD by clinical heartburn and/or acid regurgitation 5. Diagnosis GERD with under medication trial for 1-2 months before enrollment
Exclusion criteria
Exclusion criteria: 1. Hx of abdominal surgery except appendectomy and cesarean section 2. current gastric or liver cancer 3. Inflammatory bowel disease) 4. Irritable bowel syndrome) 5. Chronic constipation or abnormal bowel movement 6. Chronic liver disease/Chronic kidney disease 7. Abnormal finding of Esophagogastroduodenoscopy e.g pyloric stenosis 8. Helicobacter pylori infection 9. Esophageal motility disease; Achalasia, EGJ outflow obstruction, Diffuse esophageal spasm, Jackhammer esophagus, Absent peristalsis 10. Concurrent treatment with medication which may interfere the interpretation e.g. proton pump inhibitors, potassium competitive acid blockers, H2 blockers, prokinetics, selective serotonin reuptake inhibitors, antispasmodics, prebiotics, probiotics, antibiotics 11. Uncontrolled psychiatry disease 12. No consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TLESRs 1 day pH monitoring | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastric emptying, Gastric accommodation 1 day SPECT CT, Gastric emptying time | — |
Countries
Thailand
Contacts
Public ContactPiyakorn Poonyam
Faculty of medicine chulalongkorn university
Outcome results
None listed