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A study of the efficacy and safety of microneedle patch containing triamcinolone acetonide and hydrocortisone in the treatment of inflammatory acne

A study of the efficacy and safety of microneedle patch containing triamcinolone acetonide and hydrocortisone in the treatment of inflammatory acne

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220830003
Enrollment
28
Registered
2022-08-30
Start date
2022-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory acne inflammatory acne

Interventions

patient apply microneedle steroid patch containing hydrocortisone 250 mcg on inflammatory acne,patient apply microneedle steroid containing triamcinolone acetonide 250 mcg on inflammatory acne,patient
HC 250,TA 250,2.5% BP

Sponsors

National Research Council of Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Both male and female with age of 18 to 60 years old 3. Have inflammatory papular/pustular acne with 5 mm in size or more, for at least 4 lesions on the face

Exclusion criteria

Exclusion criteria: 1. receive topical corticosteroid or intralesional corticosteroid within 2 weeks before recruitment 2. receive ablative or non-ablative laser therapy on the face within 2 weeks before recruitment 3. receive oral corticosteroid within 8 weeks before recruitment 4. have active contact dermatitis, rash, eczema or skin infection on the face where the treatment will be located 5. History of triamcinolone, hydrocortisone, hyaluronic acid allergy or have severe intralesional corticosteroid injection adverse effects 6. are in pregnancy or breastfeeding period 7. are unable to promptly visit the office for follow-up session

Design outcomes

Primary

MeasureTime frame
Acne size 2, 3, 4, 7, 14 and 28 day Vernier caliper

Secondary

MeasureTime frame
Erythema index 2, 3, 4, 7, 14 and 28 days Antera 3D,Melanin index 2, 3, 4, 7, 14 and 28 days Antera 3D,Erythema index 2, 3, 4, 7, 14 and 28 days colorimeter,Melanin index 2, 3, 4, 7, 14 and 28 days colorimeter

Countries

Thailand

Contacts

Public ContactChanat Kumtornrut

Division of Dermatology, Faculty of Medicine, Chulalongkorn university

chanat_1@yahoo.com66814594965

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026