The healthy subjects ( more than 12 years old) who are undergoing orthodontic treatments. Fixed orthodontic appliances, dental biofilm, cariogenicity, virulence genes, dental caries
Conditions
Interventions
The orthodontist will first insert a device to keep the mouth of the patient dry and the tongue in place. Then apply an etchant to the tooth surface to prepare it for bonding. After blow drying the te
s gums.
Experimental Device
Sponsors
Walailak University, International College of Dentistry
Eligibility
Sex/Gender
All
Age
12 Years to 45 Years
Inclusion criteria
Inclusion criteria: The healthy subjects (more than 12 years old) who are undergoing orthodontic treatments at the Advanced Oral Health Center, Walailak University.
Exclusion criteria
Exclusion criteria: 1. Having a systemic disease, 2. On a long term/recent/current regimen of medications affecting salivary flow, 3. Receiving antibiotic therapy within the previous 6 months, 4. Presence severe periodontal problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cariogenic virulence gene expressions Before and after at least 6 months of intervention Real time PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| Dental biofilm maturity Before and after at least 6 months of intervention Three-tone plaque disclosing gel staining | — |
Countries
Thailand
Contacts
Public ContactKusumawadee Utispan
Faculty of Dentistry, Thammasat University
Outcome results
None listed