chronic vertigo chronic dizziness vertigo dizziness chronic vertigo
Conditions
Interventions
Kparviflora 180 mg/day with Placebo Betahistine 48 mg/day per oral for 84 days,Placebo KParviflora 180 mg/day with Betahistine 48 mg/day per oral for 84 days
Active Comparator Drug,Active Comparator Drug
K.parviflora,Betahistine
Sponsors
Argricultural Research Development Agency (Public Organization)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Individual who suffered from chronic dizziness longer than 1 month with DHI-T score over 18 2. Age 18-75 years 3. Individual who are willing and able to comply with protocol until the end of project 4. Able to read and write in Thai
Exclusion criteria
Exclusion criteria: 1. Individual who had been diagnosed with Benign Paroxysmal Positional Vertigo or Vestibular Migraine or Height Vertigo or Orthostatic Hypotension or Mental or psychiatric problem 2. Individual with abnormal proprioception including tremor and hemiplegia paraplegia 3. Individual with cardiac arrythmia 4. Individual who had been treated with and cannot withdraw EGb761 120mg/day or over or Betahistine 36 mg/day or over for longer than 72 hours 5. Individual who currently consume other herbal medicines 6. Individual who currently consume any kind of neurotic suppressor medications 7. Individual with active otitis media or perforation of tympanic membrane 8. Individual with abnormal liver and kidney function (GFR lower than 60) 9. Individual who cannot sit or stand without assistant 10. Individual with urine pregnancy test positive or in pregnancy condition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dizziness Handicap Inventory score (DHI-T) Pre-dose and at 1,28,56 and 84 day post-start DHI-T score | — |
Secondary
| Measure | Time frame |
|---|---|
| Vestibular function Pre-dose and at 84 day post-dose Posturography,VOR gain Pre-dose and at 84 day post-dose vHIT,Blood flow perfusion Pre-dose and at 56 days post-dose Optical coherence tomography angiography | — |
Countries
Thailand
Contacts
Public ContactKwanchanok Yimtae
Khon Kaen University
Outcome results
None listed