Obesity, overweight Obesity, overweight
Conditions
Interventions
2 gram of placebo (maltodextrins),2 gram Probiotic sachet (Fructooligosaccharide, Lactobacillus gasseri, Bifidobacterium lactis, Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium infanti
Placebo,Probiotic
Sponsors
NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY
National Research Council of Thailand (NRCT)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Overweight and obesity (BMI of 23-30 kg/m2)
Exclusion criteria
Exclusion criteria: Subjects with hypertension, type 2 diabetes, used medicine of previous or current treatment for gastrointestinal diseases, chronic diseases, thyroid abnormality or immune-compromising disease, hepatitis, cancer, transplant patient, used probiotic supplement 2 weeks before screening, used antibiotic medicine before 4 weeks, used medicine affecting bodyweight, energy expenditure, or glucose for last 3 months, used vitamin and mineral supplement within 6 months before screening, current smoker, alcohol drinking, pregnant or lactation were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body composition 0, 6 wk, 12 wk BMI, Weight, Waist circumference, %fat | — |
Secondary
| Measure | Time frame |
|---|---|
| gut microbiomes 0, 12 wk Sequencing bacteria analysis,Biochemical assessment 0,6,12 wk Plasma glucose, cholesterol, triglyceride, HDL, LDL, ALT, AST, BUN | — |
Countries
Thailand
Contacts
Public ContactSirichai Adisakwattana
Chulalongkorn University
Outcome results
None listed