Patients older than 18 years with clinical suspicion of CMV colitis were enrolled. The criteria for clinically suspicious of CMV colitis included: i) presence of at least one of the risk factors, including human immunodeficiency virus infection, solid organ or hematologic stem cell transplantations, hematologic malignancy, inflammatory bowel disease, taking immunosuppressive agents or chemotherapy, and critically ill with multiple comorbidities, and ii) presenting with gastrointestinal tract
Conditions
Interventions
Patients with the detection of either cytomegalic cells or IHC-CMV cells were diagnosed with CMV colitis.,Patients older than 18 years with clinical suspicion of CMV colitis but negative biopsy for CM
Diagnostic,Diagnostic,Diagnostic
CMV colitis,Non-CMV colitis ,Healthy volunteers
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients older than 18 years with clinical suspicion of CMV colitis were enrolled. The criteria for clinically suspicious of CMV colitis included: i) presence of at least one of the risk factors, including human immunodeficiency virus infection, solid organ or hematologic stem cell transplantations, hematologic malignancy, inflammatory bowel disease, taking immunosuppressive agents or chemotherapy, and critically ill with multiple comorbidities, and ii) presenting with gastrointestinal tract symptoms, including abdominal pain, gastrointestinal bleeding, diarrhea, and bowel ileus.
Exclusion criteria
Exclusion criteria: Patients who cannot undergo colonoscopy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic performance After colonoscopy Sensitivity, Specificity | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between stool, serum, tissue CMV-PCR At diagnosis Pearson correlation | — |
Countries
Thailand
Contacts
Public ContactOnuma Sattayalertyanyong
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed