Adults diagnosed with gender dysphoria (based on DSM V) by psychiatrist Age 20 to 40 years old Never used cross-sex hormone therapy transgender, transmale, cross-sex hormone
Conditions
Interventions
Adults diagnosed with gender dysphoria (based on DSM V) by psychiatrist
Age 20 to 40 years old
Never used cross-sex hormone therapy
Diagnostic
Study group
Sponsors
King Chulalongkorn Memorial Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 20 Years
Inclusion criteria
Inclusion criteria: Adults diagnosed with gender dysphoria (based on DSM V) by psychiatrist Age 20 to 40 years old Never used cross-sex hormone therapy
Exclusion criteria
Exclusion criteria: Underlying disease (Cardiovascular, stroke, VTE, DLP, OSA) Endometrial cancer, breast cancer HIV infections Bone metastasis, pathological fracture Impaired renal function (GFR<15) Parathyroid, thyroid abnormalities Anti-osteoporotic drugs (bisphosphonate, denosumab, teriparatide, SERMs) Hormonal drug use (aromatase inhibitor, OCPs) Corticosteroid use Anti-epileptic drugs (phenytoin, phenobarbital,carbamazepine)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of bone resorption markers (CTX) after 3 months of testosterone treatment 3 months different between pre and post treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of bone turnover markers ( P1NP, osteocalcin) after 6 months of testosterone treatment 6 months different between pre and post treatment,Correlation of sex hormone levels with bone turnover marker levels. 6 months different between pre and post treatment | — |
Countries
Thailand
Contacts
Public ContactSuchanant Chavaengkiat
Faculty of medicine, Chulalongkorn University
Outcome results
None listed