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Comparison of postoperative opioid consumption between Interspace between the Popliteal Artery and Capsule of the Knee block (IPACK block) and adductor canal block in patients undergoing total knee arthroplasty (TKA), a non-inferiority randomized controlled trial.

Comparison of postoperative opioid consumption between Interspace between the Popliteal Artery and Capsule of the Knee block (IPACK block) and adductor canal block in patients undergoing total knee arthroplasty (TKA), a non-inferiority randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220816002
Enrollment
28
Registered
2022-08-16
Start date
2022-07-22
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total knee replacement total knee arthroplasty spinal anesthesia IPACK block adductor canal block opioid consumption IPACK block adductor canal block opioid consumption total knee arthroplasty

Interventions

additional nerve block after spinal anesthesia, by injection of local anesthetics into adductor canal under ultrasound guidance,additional nerve block after spinal anesthesia, by injection of local a
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Adductor canal block,IPACK block

Sponsors

Strategic Wisdom and Research Institute Srinakharinwirot University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: patients scheduled for elective unilateral total knee arthroplasty (TKA) under spinal anesthesia for the first time

Exclusion criteria

Exclusion criteria: previous TKA, re-do, allergy to study drug, regional anesthesia refusal, coagulopathy, preexisting neurodeficit, chronic pain, unable to self-report pain score, unable to use PCA machine, spinal block converted to general anesthesia of any cause

Design outcomes

Primary

MeasureTime frame
cumulative morphine consumption 12 hours postoperative mg—

Secondary

MeasureTime frame
pain score 24 hours postoperative numerical rating scale—

Countries

Thailand

Contacts

Public ContactChaiyapruk Kusumaphanyo

Faculty of Medicine, Srinakharinwirot University

chaiyap@g.swu.ac.th037395085

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026