A randomized controlled trial of timing for tissue resection in Chronic limb-threatening ischemia after revascularization

Status

Unknown

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220810007

Enrollment

146

Registered

2022-08-10

Start date

2022-08-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic limb-threatening ischemia Critical limb ischemia Gangrene Debridement Tissue resection timing CLTI CLI Debridement tissue resection timing

Interventions

Chronic limb-threatening ischemia patient after successful revascularization undergone tissue resection in the same operation or within 14 days ,Chronic limb-threatening ischemia patient after success

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

Concurrent tissue resection,Delayed tissue resection

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed Chronic limb-threatening ischemia 2. Successful revascularization 3. Accept informed consent

Exclusion criteria

Exclusion criteria: 1. Moderate wound infection before allocation 2. Systemic inflammatory response syndrome before allocation

Design outcomes

Primary

Measure	Time frame
Wound healing time at the date of wound healed time after tissue resection to the date of wound completely healed	—

Secondary

Measure	Time frame
Wound infection rate assess every follow-up visit until the wound healed Wound characteristic,Major adverse limbs event Until date of wound healed reoperation (revascularization/tissue resection), Major amputation,Major Adverse Cardiovascular Events Until date of wound healed Myocardial infarction, Stroke, Death,Length of hospital stay until discharge from first tissue resection operation Cumulative hospitalized days	—

Measure

Time frame

Wound infection rate assess every follow-up visit until the wound healed Wound characteristic,Major adverse limbs event Until date of wound healed reoperation (revascularization/tissue resection), Major amputation,Major Adverse Cardiovascular Events Until date of wound healed Myocardial infarction, Stroke, Death,Length of hospital stay until discharge from first tissue resection operation Cumulative hospitalized days

—

Countries

Thailand

Contacts

Public ContactSaharath Pongmongkol

Faculty of Medicine Ramathibodi Hospital, Mahidol University

sp_sam3@hotmail.com0876945709

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026