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The success rate of lumbar puncture in neonates using ultrasound-assisted versus traditional technique: a randomized controlled trial

The success rate of lumbar puncture in neonates using ultrasound-assisted versus traditional technique: a randomized controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220806002
Enrollment
156
Registered
2022-08-06
Start date
2022-08-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonates with corrected age less than or equal to 30 days Infant, newborn Ultrasound Lumbar puncture

Interventions

Patient is positioned in right or left lateral decubitus with hip and knee flexion. Ultrasound scan is performed by neonatologists and neonatology fellows using linear high-frequency transducer (probe
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Ultrasound-assisted lumbar puncture,Traditional lumbar puncture

Sponsors

Dr Walaiporn Bowornkitiwong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 30 Days

Inclusion criteria

Inclusion criteria: 1. neonates who are admitted in neonatal ward 2. neonates corrected age less than or equal 30 days 3. neonates who will undergo lumbar puncture

Exclusion criteria

Exclusion criteria: 1. spine or spinal cord abnormality 2. has ventriculoperitoneal shunt or ventriculostomy in situ 3. previously underwent lumbar puncture 4. IVH grade II or above 5. patients who have contraindication for LP eg. increased intracranial pressure, skin infection at puncture site 6. platelet < 50,000/microliter 7. unstable vital signs 8. legal guardian unable to communicate in Thai

Design outcomes

Primary

MeasureTime frame
first attempt success rate without trauma from starting to completion of the first attempt of LP CSF at least 2 ml in the first attempt and RBC less than or equal to 1000 per milliliter

Secondary

MeasureTime frame
first-2-attempt success rate without trauma from starting to completion of the second attempt of LP CSF at least 2 ml and RBC less than or equal to 1000 per milliliter,overall success rate from starting to completion of LP CSF at least 2 ml and RBC less than or equal to 1000 per milliliter,number of attempts from starting to completion of LP manual counting

Countries

Thailand

Contacts

Public ContactWalaiporn Bowornkitiwong

Faculty of Medicine Siriraj Hospital

walbj@hotmail.com66894223604

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026