FindTrial
Sign In

Pain reduction efficacy of intra-articular platelet-rich plasma injection in comparison with intra-articular corticosteroid injection in knee osteoarthritis with delayed joint replacement, randomized controlled trial

Pain reduction efficacy of intra-articular platelet-rich plasma injection in comparison with intra-articular corticosteroid injection in knee osteoarthritis with delayed joint replacement, randomized controlled trial

Status
Unknown
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220801003
Enrollment
80
Registered
2022-08-01
Start date
2024-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage osteoarthritis of knee with delayed joint replacement surgery related with increased pain and impaired activity function. PRP and Steroid Injection could reduced pain and improved function. Advance Stage OA Knee, Delayed Surgery, PRP Injection, Steroid Injection

Interventions

Single Spin PRP Intraarticular Injection,Triamcinolone 20 mg intraarticular injection
Active Comparator Drug,Active Comparator Drug
PRP injection,Stroroid Injection

Sponsors

Navamindradhiraj University Research Fund
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Primary OA knee KL III-IV 2.Age 55 to 80 years 3.TKA Waiting List > 6 months

Exclusion criteria

Exclusion criteria: Allergy to drug in study Previous interventions on the knee joint Impair Renal Function (GFR < 30 ml/min) Chronic pain not related to knee joint Blood clotting disorders or treated with anticoagulants Uncontrolled diabetes (Hb A1C in last 3 months >= 8%) Hb < 12 mg/dl or Platelet < 150,000 Local wound infection at injection site Autoimmune diseases Pregnancy or Breastfeeding Chronic Liver Disease

Design outcomes

Primary

MeasureTime frame
Pain Score 2 weeks, 6 weeks, 12 weeks, 24 weeks NRS—

Secondary

MeasureTime frame
Functional Outcome 2 weeks, 6 weeks, 12 weeks, 24 weeks WOMAC,Complication 2 weeks, 6 weeks, 12 weeks, 24 weeks Incidence—

Countries

Thailand

Contacts

Public ContactIttiwat Onklin

Faculty of Medicine, Vajira Hospital, Navamindradhiraj University

ittiwat@nmu.ac.th0946954166

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026