Effectiveness of Aerosol Filtration by Mechanical Filter, Electrostatic Filter, and Electrostatic Filter with Heat Moisture Exchanger in Healthy volunteers Nebulized with Normal Saline

Status

Unknown

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220729002

Enrollment

Registered

2022-07-29

Start date

2022-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Filters&#039

Interventions

Volunteers breathing through normal saline nebulizer set for 5 minutes, which connected to oxygen flow 8 LPM and mechanical filter. Number of particles/m2 and system pressure will be recorded by resea

Active Comparator Device,Active Comparator Device,Active Comparator Device,No Intervention Device

Mechanical Filter,Electrostatic Filter,Electrostatic Filter with Heat Moisture Exchanger,no filter

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: age 20-65 years old healthy (ASA I-II) consented

Exclusion criteria

Exclusion criteria: respiratory symptoms respiratory diseases (COPD, asthma) pregnancy cardiovascular diseases allergic to normal saline consent withdrawn

Design outcomes

Primary

Measure	Time frame
number of particles every 1 minute until 5 minutes particle counter device	—

Secondary

Measure	Time frame
Resistance across filter every 1 minute until 5 minutes Anesthetic machine	—

Countries

Thailand

Contacts

Public ContactJittiya Watcharotayangul

Faculty of Medicine Ramathibodi Hospital Mahidol University

jittiya.wat@mahidol.edu0818400486

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026