The Comparison between Different Doses of LetibotulinumtoxinA and Normal Saline for Intradermal Face-Lifting: A Split-Face Randomized Controlled Trial

The comparison between intradermal injection of Botulinumtoxin A and normal saline for face-lifting: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220720011

Enrollment

Registered

2022-07-20

Start date

2017-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial laxity Intradermal injection LetibotulinumtoxinA Face-lifting

Interventions

1. Participants were taken pictures and 3d pictures 2. Participants faces were divided into left and right by randomize 3. One side of the face was treated by using LetibotulinumtoxinA total 50 units

Experimental Drug

Toxin for face lifting

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: mild facial laxity

Exclusion criteria

Exclusion criteria: 1. pregnant or lactating woman 2. Having allergic to botulinum toxin 3. Having the skin disease around the treated area 4. Using an energy-based device or other interventions around treated area 12 months prior

Design outcomes

Primary

Measure	Time frame
Subject self assessment score 2 weeks 6 points scale,Physicians assessment score 2 weeks 6 points scale	—

Secondary

Measure	Time frame
Sebum production before treatment, 2 weeks Sebumeters machine,Antera3d measure pore before treatment, 2 weeks pore size	—

Countries

Thailand

Contacts

Public ContactSurachet Sirisuthivoranunt

Faculty of Medicine Siriraj Hospital, Mahidol University

siri.surachet@gmail.com024199933

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026