Healthy L-ascorbic acid, ultraglycans, melatonin, skin elasticity
Conditions
Interventions
Patient were treated daily with Topical facial cream containing L-ascorbic acid and ultraglycans in combination with a topical night serum formulated with melatonin for 8 weeks. Then they were instruc
Experimental Drug
Topical facial cream day containing L-ascorbic acid and ultraglycans in combination with a topical night serum formulated with melatonin
Sponsors
HACK LAB LIMITED PARTNERSHIP
Eligibility
Sex/Gender
All
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 35-55 years 2. Apply cream for 1 month
Exclusion criteria
Exclusion criteria: 1. Patient who are pregnant or lactating 2. Patient who take oral medicine or topical substance for whitening agents within 1 month or got surgical treatment to treat erythema or hyperpigmentation in 6 month 3. Allergy to L-ascorbic acid, ultraglycans and melatonin 4. Patient who take oral antioxidants 5. Patient with other skin disease, or having infection at the area of treatment 6. Immunocompromised patients 7. Patient with Herpes Simplex infection 8. Alcoholic or current smoking patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Elasticity Baseline,4,8,12 weeks Cutometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin hydration Baseline,4,8,12 weeks Corneometer,Transepidermal water loss Baseline,4,8,12 weeks Tewameter,Melanin and erythema index Baseline,4,8,12 weeks Mexameter,Skin brightening Baseline,4,8,12 weeks Colorimeter,Average melanin Baseline,4,8,12 weeks Antera,Skin texture Baseline,4,8,12 weeks Antera,Skin depression Baseline,4,8,12 weeks Antera,Safety 4,8,12 weeks Adverse effect,Percent improvement 4,8,12 weeks Patient improvement scale | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed