Patients who are suspected of having oral potentially malignant disorders or non-healing ulcer more than 2 weeks without any identifiable cause requiring biopsy Electrospun, Oral potentially malignant disorders, Toluidine blue, Sensitivity, Specificity
Conditions
Interventions
Apply electrospun containing toluidine blue at lesion, biopsy for histopathologic evaluation
Experimental Other
Toluidine blue staining
Sponsors
Royal College of Dental Surgeons
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male or female subjects age > 20 years old 2. Patients who are suspected of having oral potentially malignant disorders 3. Patients with non-healing ulcer more than 2 weeks without any identifiable cause 4. Patients who can be followed up 5. Patients who give their consent for the study
Exclusion criteria
Exclusion criteria: 1. Patients with severe systemic diseases that interfere with or contraindication to the biopsy procedure 2. Patients with the presence of obvious invasive carcinomas 3. Patients who abandoned treatment 4. Patients who refuse the study 5. Patients who are allergic to toluidine blue, acetic acid, polyvinylpyrrolidone or local anesthetic agents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Staining of oral potentially malignant disorders by the use of electrospun containing toluidine blue Time of treatment Visual examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Histopathological diagnosis Time of treatment Histopathological evaluation | — |
Countries
Thailand
Contacts
Public ContactJITJIROJ ITTICHAICHAROEN
Faculty of Dentistry, Chiang Mai University
Outcome results
None listed