Apneic oxygenation with low-flow nasal cannula for rapid sequence intubation in pediatric patients: a randomized-controlled trial

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220711001

Enrollment

220

Registered

2022-07-11

Start date

2022-09-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age 0-6 year ASA 1-3 General anesthesia with rapid sequence induction and intubation RSII, low flow nasal cannula, pediatric anesthesia

Interventions

Infants insufflate O2 flow 5 LPM. via nasal cannula 1-6 years insufflate O2 flow 10 LPM. via nasal cannula ,nasal cannula without Oxygen

Experimental Drug,Placebo Comparator No treatment

Oxygen low flow nasal cannula,control

Eligibility

Sex/Gender

All

Age

1 Hours to 6 Years

Inclusion criteria

Inclusion criteria: Age 0-6 year ASA 1-3 General anesthesia with rapid sequence induction and intubation

Exclusion criteria

Exclusion criteria: Preoperative SpO2 < 95% Preoperative oxygen supplement Expected difficult airway management History of allergic to midazolam, fentanyl, succinylcholine, thiopental Body temperature > 37.5 C

Design outcomes

Primary

Measure	Time frame
dasauration SpO2 less than 92% SpO2	—

Secondary

Measure	Time frame
time to loweat SPO2 time to lowest SPO2 SPO2	—

Countries

Thailand

Contacts

Public ContactNaiyana Aroonpruksakul

Faculty of Medicine, Siriraj Hospital, Mahidol University

nging2day@gmail.com0909905281

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026