hyperphosphatemia decreased kidney function hyperphosphatemia kidney function acute kidney injury chronic kidney disease phosphate magnesium glomerular filtration rate
Conditions
Interventions
Hyperphosphatemic subjects were given MgCO3 6 mg/kgBW/24 hours for 3 months,Hyperphosphatemic subjects were given Saccharum Lactis 6 mg/kgBW/24 hours
Treatment,Treatment
Magnesium group,Saccharum Lactis group
Sponsors
Dr Soetomo General Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: phosphate level above 6.51 mg/dL (age 2-5 years old); above 5.8 mg/dL (age 6-12 years old); or above 4.6 mg/dL (age 13-18 years old)
Exclusion criteria
Exclusion criteria: 1. currently on hemodialysis or peritoneal dialysis 2. estimated glomerular filtration rate less than 15 ml/min/1.73 m2 3. serum magnesium level above 2.5 mg/dL 4. allergic to magnesium supplementation 5. history of severe gastrointestinal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| estimated glomerular filtration rate after 1 month, 2 months, and 3 months of intervention 1.serum creatinine analyzed using Siemens Dimension Exl 200; 2.calculate eGFR (k x height in cm/serum Cr) k : 0.55 in 2-13 years old child and girl above 13 years old. k : 0.7 in boy 13-18 years old,serum phosphate level after 1 month, 2 months, and 3 months of intervention inorganic phosphate in serum analyzed using Siemens Dimension Exl 200 | — |
Secondary
| Measure | Time frame |
|---|---|
| serum magnesium level after 1 month, 2 months, and 3 months of intervention magnesium in serum analyzed using Siemens Dimension Exl 200,adverse event during intervention interview and physical examination | — |
Countries
Indonesia
Contacts
Public ContactGlabela Pandango
Airlangga University
Outcome results
None listed