Postmenopausal women Postmenopausal, soy extract, anti-skin aging
Conditions
Interventions
Soy extract recipe product, administered 2 capsules twice daily (12 weeks). ,The placebo will be the instant powder, prepared in an identical appearance and flavor but without soy extract, administere
Soy extract recipe product,Placebo
Sponsors
Chiang Mai University
Eligibility
Sex/Gender
Female
Age
48 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Healthy volunteers (based on medical history and physical examination) and > 1 year postmenopausal, 2) FSH > 30 mU/mL, 3) Body mass index (BMI) 18-30 kg/m2.
Exclusion criteria
Exclusion criteria: 1) Known contraindication or hypersensitivity to soybean and other soya products, 2) Treatment with estrogens or isoflavone for the previous 6 months, 3) Taking retinoids, vitamin, minerals, herbal substances, antibiotics, steroids, or immunosuppressants within 3 months prior to enrollment, 4) A history of chronic disorders related to renal, liver, cardiovascular, brain, GI, blood or thyroid, 5) Regular consumption of alcohol, cigarette smoking, or recreational drugs use/addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Evaluation at 0 and 12 weeks after end of the intervention Visiometer, Visiopor, Corneometer, Colorimeter, Cutometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life at 12 weeks after end of the intervention The MENQOL questionnaire,Vasomotor symptoms at 12 weeks after end of the intervention The Modified Kupperman Index,Bone turnover markers at 12 weeks after end of the intervention Osteocalcin, TotalP1NP and Beta-crosslaps | — |
Countries
Thailand
Contacts
Public ContactSupanimit Teekachunhatean
Chiang Mai university
Outcome results
None listed