Lumbar HNP/spinal stenosis with Radiculopathy Lumbar HNP/spinal stenosis with Radiculopathy
Conditions
Interventions
1. Inhaled methoxyflurane 3 mL (one bottle) 4 minutes before procedure
2. 1% Lidocaine with adrenaline for Local infiltration 1 cc per 1 attempt
3. Triamcinolone acetonide 40 mg/ml 0.25 cc (10 mg) +
Active Comparator Drug,Placebo Comparator Drug
Sponsors
Faculty of Medicine Thammasat University
Daiichi Sankyo (Thailand)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient diagnosed Lumbar HNP/spinal stenosis with Radiculopathy (1-3 Level , Dx by MRI ,conservative > 3 months) Age >18 years Understand the protocol and volunteered to join the study
Exclusion criteria
Exclusion criteria: Cannot undertaken SNRB injection/not co-operate to use Inhaled methoxyflurane History of Traumatic back pain , Spinal surgery , Active infection Severe degenerative spine Pregnancy /Lactation Allergy to study drugs (Inhaled methoxyflurane & other drugs in standard order) Renal insufficiency (Creatinine clearance <30ml/min) History of cardiovascular instability , lung or respiratory impairment , stroke or intracranial surgery Abnormal liver function (2.5xULN) Established malignant hyperthermia Last administration of methoxyflurane
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain during operation Visual analogue scale | — |
Secondary
| Measure | Time frame |
|---|---|
| pain post-use inhaled methoxyflurane ( at 0 min ,30 min , 60 min , 90 min , 120 min ) Visual analogue scale,Adverse effect at 2 weeks after end of the intervention adverse effect choices,Satisfactory during operation Satisfactory score | — |
Countries
Thailand
Contacts
Public ContactThanadol Techavitoonwong
Faculty of Medicine, Thammasat University
Outcome results
None listed