Application of platelet-rich fibrin membrane versus amniotic membrane transplantation after pterygium excision

Status

Unknown

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220627006

Enrollment

Registered

2022-06-27

Start date

2022-06-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary pterygium pterygium, recurrent pterygium, pterygium excision, Platelet rich fibrin, amniotic

Interventions

After routine pterygium excision, PRF membrane will be sutured with Vicryl 8-0. PRF membrane obtained by drawing blood and put in centrifuge 1300 rpm for 14 mins then press with PRF box and cut to fit

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

PRF membrane,Amniotic membrane

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with primary pterygium

Exclusion criteria

Exclusion criteria: Bi headed pterygium Autoimmune disease - SLE, Rheumatoid arthritis, scleroderma, Sjrogen syndrome Pseudopterygium

Design outcomes

Primary

Measure	Time frame
Pterygium recurrent 1 Year Pterygium recurrent based on photograph	—

Secondary

Measure	Time frame
Pterygium recurrent 6 Month Pterygium recurrent based on photograph,Pain postoperative NRS pain scale,Surgical time intraoperative time,Complication 1 Year record,Wound closure 1 week Slit lamp evaluation of epithelial defect using fluorescein	—

Countries

Thailand

Contacts

Public ContactNathapon Treewipanon

Faculty of Medicine, Naresuan University

nathapont@nu.ac.th055965056

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026