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Efficacy of tranexamic acid on Post-operative periorbital ecchymosis and edema in upper blepharoplasty : A Prospective randomized double-blind study

Efficacy of tranexamic acid on Post-operative periorbital ecchymosis and edema in upper blepharoplasty : A Prospective randomized double-blind study

Status
Unknown
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220624007
Enrollment
60
Registered
2022-06-24
Start date
2022-07-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patient undergo upper blepharoplasty in Srinagarind Hospital transamine,TXA,blepharoplasty,upper blepharoplasty,ecchymosis,edema,periorbital edema,periorbital ecchymosis,tranexamic acid

Interventions

tranexamic acid 1g (250mg 4 tab ) before 2 hours and tranexamic acid (250mg ) 1 tab 3 time a day for 5 day
Experimental Drug
tranexamic acid

Sponsors

faculty of medicine khon kaen university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.patient undergo upper blepharoplasty at Srinagarind Hospital 2.patient participation in this clinical trials 3.patient don't have history of tranexamic allergy

Exclusion criteria

Exclusion criteria: 1.History of previous undergo upper blepharoplasty 2.Infected wound 3.Underlying disease associated with wound healing such as Diabetes,immunocompromised 4.Patient undergo both upper and lowwer blepharoplasty 5.Underlying disease associated with thrombosis such as thromboembolic event, hemoglobinopathy 6.Bleeding tendency diasease such as coagulopathy ,hemolytic disease 7.Chronic kidney disease 8.Patient had history used NSAID,anticoagulant, anti platelet with in 7 day 9.patient who has complication after surgery

Design outcomes

Primary

MeasureTime frame
periorbital ecchymosis 7 day after operation periorbital ecchymois scale

Secondary

MeasureTime frame
periorbital edema 7 day after operation periorbital edema scale

Countries

Thailand

Contacts

Public ContactDin Tangkanobol

Faculty of Medicine, Khon Kaen University

dintsx@gmail.com0855559532

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026