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Evaluation of Endodontic treatment outcome for the Maxillary First Molars with and without operating microscope using Cone Beam Computed Tomography: Randomized Clinical Trial

Evaluation of Endodontic treatment outcome for the Maxillary First Molars with and without operating microscope using Cone Beam Computed Tomography: Randomized Clinical Trial

Status
Unknown
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220624003
Enrollment
90
Registered
2022-06-24
Start date
2022-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

this trial is conducted on mature first maxillary molars with the diagnosis of carious involvement of the pulp, with apical periodontitis, that show periapical change (radiographic PDL space widening, radiolucency) with/without Schneiderian membrane epithelium thickening on preoperative CBCT scan. Age range of patients to be included in the study is (18-65) years. CBCT, Operating Microscope, maxillary first molars, second mesiobuccal canal, Schneider membrane epithelium .

Interventions

root canal treatment in this group will be performed with the aid of magnification using operating microscope,root canal treatment in this group will be performed conventionally (without microscope)
Active Comparator Device,Active Comparator Procedure/Surgery
microscopic endodontic treatment,conventional endodontic treatment

Sponsors

researcher funding
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: mature first maxillary molars with the diagnosis of carious involvement of the pulp, with acute or chronic apical periodontitis, that show periapical change (radiographic PDL space widening, radiolucency) with without Schneiderian membrane epithelium thickening on preoperative CBCT scan. Age range of patients to be included in the study is (18-65) years.

Exclusion criteria

Exclusion criteria: Exclusion criteria: pregnancy, immunosuppression, patients received radiotherapy, uncontrolled diabetic patients, use of corticosteroids, patients taking bisphosphonates , unrestorable teeth , teeth with periodontal probing depths greater than 3 mm, uncontrolled periodontal disease, teeth with severely curved roots according to Shneider's classification, use of corticosteroids, root canal perforations if occur during endodontic treatment, separated instruments, vertical root fractures, signs of root resorption.

Design outcomes

Primary

MeasureTime frame
periapical change (lesion size, periodental ligament space widening) at 12 months after the end of intervention linear measurements in millimeter on coronal and sagittal section of cone beam computed tomography

Secondary

MeasureTime frame
thickness of Schneiderian membrane epithelium associated with periapical pathology following endodontic treatment. at 12 months after the end of intervention linear measurements in millimeter on coronal and sagittal section of cone beam computed tomography

Countries

Iraq

Contacts

Public ContactRaghad AlHashimi

University of Baghdad/ College of Dentistry

raghadalhashimi@codental.uobaghdad.edu.iq009647727363440

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026