Healthy human volunteers Alcohol-based hand sanitizer Hand hygiene Ethanol
Conditions
Interventions
Spray formulation ABHRs consisting of
Ethanol 80% volume by volume
Glycerol 1.45% volume by volume
Hydrogen peroxide 0.125% volume by volume
3 mL of ABHRs applying at least 10 times per day for 21 con
Active Comparator Other,Sham Comparator No treatment
Spray formulation ABHRs,Gel formulation ABHRs
Sponsors
Faculty of Medicine, Srinakharinwirot University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age of more than or equal to 18 years old 2. Able to be followed up as appointed 3. Willing to give an informed consent
Exclusion criteria
Exclusion criteria: 1. Having history of allergy to the component of product in study which symptoms are pruritic papules without burning sensation or pain at area contacting with alcohol-based hand sanitizers 2. Having hand eczema 3. Currently using an anti-inflammatory agent including tropical, oral, or injected form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hand irritation Day 0, 3, 5, 7, 14, 21 Subjective Larson skin assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Hand irritation Day 0, 3, 5, 7, 14, 21 Frosch and Kligman observer skin assessment,Skin barrier status Day 0, 3, 5, 7, 14, 21 Transepidermal water loss,Skin hydrating status Day 0, 3, 5, 7, 14, 21 Skin capacitance,Patient tolerability and acceptability Day 21 WHO protocol for evaluation and comparison of tolerability and acceptability | — |
Countries
Thailand
Contacts
Public ContactChananya Suwanchai
Srinakharinwirot University
Outcome results
None listed