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Efficacy and Safety of Cannabidiol Oil in Psoriasis: A Randomized, Double-Blind, Placebo-Controlled Trial

Efficacy and Safety of Cannabidiol Oil in Psoriasis: A Randomized, Double-Blind, Placebo-Controlled Trial

Status
Unknown
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220622002
Enrollment
28
Registered
2022-06-22
Start date
2022-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis Psoriasis, Chronic plaque type psoriasis

Interventions

cannabidiol (CBD) dose 30 mg per dose, 0.3 ml, per oral, twice a day, total duration of 12 weeks,Placebo dose, 0.3 ml, per oral, twice a day, total duration of 12 weeks
cannabidiol (CBD),Placebo

Sponsors

National Research Council of Thailand (NRCT)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Chronic plaque type psoriasis patients - Age 18-80 years old - No change of systemic treatment with in last 1 month

Exclusion criteria

Exclusion criteria: - Current biologic therapy - Active psychiatric problem with in last 1 year - Active hepatic or renal diseases - Pregnancy or lactation - Allergy to cannabidiol (CBD) or CBD derivatives

Design outcomes

Primary

MeasureTime frame
Severity of psoriasis at 12 weeks after end of the intervention Psoriasis Area Severity index

Secondary

MeasureTime frame
Itching at 12 weeks after end of the intervention visual analog scale of itch,Quality of life at 12 weeks after end of the intervention Dermatology Life Quality Index ,Depression/anxiety/stress at 12 weeks after end of the intervention Depression anxiety stress scales,Sleep quality at 12 weeks after end of the intervention the Pittsburgh sleep quality index,Sleep efficiency at 12 weeks after end of the intervention Sleep efficiency percentage

Countries

Thailand

Contacts

Public ContactWanjarus Roongpisuthipong

Navamindradhiraj university

wanjarus@nmu.ac.th022443000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026