A comparison of technique between combined adductor canal block with tibial nerve block and single injection adductor canal block alone for postoperative pain after total knee arthroplasty: a randomized controlled trial study

A comparison of technique between combined adductor canal block with tibial nerve block and single injection adductor canal block alone for postoperative pain after total knee arthroplasty: a randomized controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220622001

Enrollment

Registered

2022-06-22

Start date

2022-07-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after total knee artroplasty total knee arthoplasty, adductor canal block, tibial nerve block, pain control

Interventions

adductor canal block with 0.25%bupivacaine with adreanaline(1:200:000) total 15 ml,adductor canal block with 0.25%bupivacaine with adrenaline(1:200:000) total 15 ml and tibial nerve block with 0.25%b

No Intervention Procedure/Surgery,Experimental Procedure/Surgery,Experimental Procedure/Surgery

adductor canal block,adductor canal block+tibial nerve block,adductor canal block+tibial nerve block

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.age between 18-75 years 2.ASA 1-3

Exclusion criteria

Exclusion criteria: 1.Total knee arthroplasty both knee or redo operations 2.body weight below 30kilograms 3.allergy to drug in study 4.abnormal neuro exam about leg 5.contraindication for spinal block or regional block 6.patients have communication problem 7.can not operate with spinal block only

Design outcomes

Primary

Measure	Time frame
accumulated morphine consumption 24 hours milligrams	—

Secondary

Measure	Time frame
accumulated morphine consumption 6,12,48 hours milligrams,pain score 6, 12, 24, 48 hr numeric rating scale at rest and during movement,sensory blockade of tibial nerve and common peroneal nerve distribution 30 minutes after block A grading of sensory loss defined as grade 0 (no perception of touch nor cold sensation), grade1 (feeling of a normal touch but no cold perception), grade2 (normal sensation),motor blockade of tibial nerve and common peroneal nerve distribution 30 minutes after block A grading of motor defined as grade0 (unable to resist resistance), grade1 (able to resist some resistance), and grade2 (normal power),Adverse event such as post-operative nausea and vomiting, over sedation, respiratory depression, and local anesthetic systemic toxicity from the time of peripheral nerve block until 48 hours postoperatively present/ absent	—

Measure

Time frame

accumulated morphine consumption 6,12,48 hours milligrams,pain score 6, 12, 24, 48 hr numeric rating scale at rest and during movement,sensory blockade of tibial nerve and common peroneal nerve distribution 30 minutes after block A grading of sensory loss defined as grade 0 (no perception of touch nor cold sensation), grade1 (feeling of a normal touch but no cold perception), grade2 (normal sensation),motor blockade of tibial nerve and common peroneal nerve distribution 30 minutes after block A grading of motor defined as grade0 (unable to resist resistance), grade1 (able to resist some resistance), and grade2 (normal power),Adverse event such as post-operative nausea and vomiting, over sedation, respiratory depression, and local anesthetic systemic toxicity from the time of peripheral nerve block until 48 hours postoperatively present/ absent

—

Countries

Thailand

Contacts

Public ContactNaruemon Vattanasiriporn

FACULTY OF MEDICINE, KHON KAEN UNIVERSITY

anny_nana@hotmail.com0878620089

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026