PD patient with OH Orthostatic hypotension, Nocturnal hypertension, Supine hypertension, Parkinson'
Conditions
Interventions
PD patients who have been office BP measurements demonstrating a drop of at least 20 mmHg of SBP or 10 mmHg of DBP after 3 min of standing from a supine position
Treatment
PD patients with orthostatic hypotension
Sponsors
Department of Medicine, Faculty of Medicine, Chulalongkorn University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. patients who have been office BP measurements demonstrating a drop of at least 20 mmHg of SBP or 10 mmHg of DBP after 3 min of standing from a supine position at least two visited at the outpatient clinic, 2. stable dosage of antiparkinsonian and antihypertensive medications at least 4 weeks prior to the study, 3. able to stand at least three minutes for BP measured
Exclusion criteria
Exclusion criteria: Patients with comorbidities of chronic heart failure, chronic renal failure, amyloidosis, active malignancies, other secondary forms of autonomic diseases, diabetes mellitus or diseases potentially associated with autonomic dysfunction, and parkinsonism plus syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnitude of orthostatic hypotension at the end of intervention 24 hour BP monitoring | — |
Secondary
| Measure | Time frame |
|---|---|
| nocturnal blood pressure at the end of intervention 24-hour BP monitoring,Symptom of orthostatic hypotension at the end of intervention orthostatic hypotension questionnaire | — |
Countries
Thailand
Contacts
Public ContactTittaya Prasertpan
Chulalongkorn University
Outcome results
None listed