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Efficacy of probiotic food supplement in human volunteers with anti-aging effects of the skin

Efficacy of probiotic food supplement in human volunteers with anti-aging effect of the skin

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220621003
Enrollment
120
Registered
2022-06-21
Start date
2021-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers Probiotics Bifidobacterium animalis Lactobacillus reuteri anti-aging skin hydration transepidermal water loss skin elasticity wrinkles

Interventions

oral Lactobacillus reuter TF7 capsule twice daily,oral Bifidobacterium animalis TA7 capsule twice daily,oral Lactobacillus reuter TF7 capsule combined with oral Bifidobacterium animalis TA7 capsule
oral Lactobacillus reuter TF7 capsule ,oral ifidobacterium animalis TA7 capsule ,oral Lactobacillus reuter TF7 capsule combined with oral Bifidobacterium animalis TA7 capsule,Isomalt

Sponsors

CPF Food Research and Development Center Company Limited
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-60 years both men and women 2. Healthy volunteers

Exclusion criteria

Exclusion criteria: 1. Skin infection 2. Taking or applying skin hydration agents 3. Current antibiotic taking 4. Pregnancy and breastfeeding 5. Smoking 6. Allergic to probiotics 7. Products causing skin dehydration such as oral or topical retinoid

Design outcomes

Primary

MeasureTime frame
Skin hydration follow up every 4 week for 12 weeks Corneometer

Secondary

MeasureTime frame
Transepidermal Water Loss follow up every 4 week for 12 weeks Tewameter,Skin Elasticity follow up every 4 week for 12 weeks Cutometer,Facial Skin Wrinkles follow up every 4 week for 12 weeks Indentation index via Antera 3D,Patient satisfaction follow up weekly for 12 weeks Visual analogue scale

Countries

Thailand

Contacts

Public ContactChantaluck Muennarong

Faculty of Medicine, Srinakharinwirot University

Christiantam155@gmail.com0834950155

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026