Healthy volunteers Probiotics Bifidobacterium animalis Lactobacillus reuteri anti-aging skin hydration transepidermal water loss skin elasticity wrinkles
Conditions
Interventions
oral Lactobacillus reuter TF7 capsule twice daily,oral Bifidobacterium animalis TA7 capsule twice daily,oral Lactobacillus reuter TF7 capsule combined with oral Bifidobacterium animalis TA7 capsule
oral Lactobacillus reuter TF7 capsule ,oral ifidobacterium animalis TA7 capsule ,oral Lactobacillus reuter TF7 capsule combined with oral Bifidobacterium animalis TA7 capsule,Isomalt
Sponsors
CPF Food Research and Development Center Company Limited
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years both men and women 2. Healthy volunteers
Exclusion criteria
Exclusion criteria: 1. Skin infection 2. Taking or applying skin hydration agents 3. Current antibiotic taking 4. Pregnancy and breastfeeding 5. Smoking 6. Allergic to probiotics 7. Products causing skin dehydration such as oral or topical retinoid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin hydration follow up every 4 week for 12 weeks Corneometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Transepidermal Water Loss follow up every 4 week for 12 weeks Tewameter,Skin Elasticity follow up every 4 week for 12 weeks Cutometer,Facial Skin Wrinkles follow up every 4 week for 12 weeks Indentation index via Antera 3D,Patient satisfaction follow up weekly for 12 weeks Visual analogue scale | — |
Countries
Thailand
Contacts
Public ContactChantaluck Muennarong
Faculty of Medicine, Srinakharinwirot University
Outcome results
None listed