healthy volunteers Benjalokawichienon, immunity
Conditions
Interventions
BLWC water extract 1000 milligrams per day (4 times a day) for 14 days,BLWC water extract 2000 milligrams per day (4 times a day) for 14 days,Placebo 2000 milligrams per day (4 times a day) for 14 da
BLWC low dose,BLWC lohigh dose,Placebo
Sponsors
National lnnovation Agency
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1 Male and female participants aged between 20 to 45 years 2 No underlying disease; 3 Able to read and write in Thai; and 4 All participants will be informed both verbally and in writing of the possible risks and adverse events which may occur during the study and must sign the written consent forms to participate in the study. 5 History of COVID-19 infection
Exclusion criteria
Exclusion criteria: 1) Physical examination revealed clinically significant abnormalities 2) Receiving any vaccination within the past 3 months; 3) Receiving any immunosuppressants such as corticosteroids, cyclosporin, tacrolimus, methotrexate, or monoclonal antibodies within the last 3 months; 4) Receiving any herbal medication within the last 1 week; 5) Abnormal EKG 6) Having a history of end stage of hepatic or renal disease; 7) Having a history servere allergy 8) smoking 9) pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safety profile Day0, day8, day15 Blood chemistry | — |
Secondary
| Measure | Time frame |
|---|---|
| Immune cells day1, day3,day8,day15 white blood cell differentiation ,Inflamatory cytokines day1, day3,day8,day15 Blood ELISA test,antioxidant day1, day3,day8,day15 plasma for antioxidant assay | — |
Countries
Thailand
Contacts
Public ContactSaranyapin Poitknoand
Chaing Mai University
Outcome results
None listed