Characterization of circulating tumour cells undergoing epithelial-mesenchymal transition in hepatocellular carcinoma and its revlevance in tumor staging modalities

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20220613008

Enrollment

Registered

2022-06-13

Start date

2022-03-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma Circulating tumor cells, Hepatocellular carcinoma, Epithelial-mesenchymal transition, Phenotype, prognosis

Interventions

HCC patients with detectable of epithelial subtype in peripheral blood samples which are conducted by immunofluorescent staining and divided into epithelial, hybrid and mesenchymal subtypes. The epith

Other,Other

EMT-CTCs subtype positive,EMT-CTCs subtype negative

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The HCC patients are recruited at Maharaj Nakorn Chiang Mai Hospital. Principal inclusion criteria are: 1) Patients diagnosed with HCC according to American Association for Study of Liver Disease (AASLD) and 2) no prior anti-cancer treatment.

Exclusion criteria

Exclusion criteria: Protocols exclude HCC patients with a history of other cancer.

Design outcomes

Primary

Measure	Time frame
Clinicopathological features of patients at the time of diagnosis Hospital record	—

Secondary

Measure	Time frame
Disease free survival 12 months Kaplan-Meier method	—

Countries

Thailand

Contacts

Public ContactSanthasiri Orrapin

Chiang Mai University

santhasiri.or@cmu.ac.th053934674

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026