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Different injection techniques of hyaluronic acid filler for lip augmentation: A randomized left-right comparative study

Different injection techniques of hyaluronic acid filler for lip augmentation: A randomized left-right comparative study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220608001
Enrollment
30
Registered
2022-06-08
Start date
2022-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Participants who desired to have a lip filler Belotero, Blunt, Merz, Microcanula, Sharp

Interventions

One side of upper lip was augmented with a total volume of 0.3 ml of HA filler (Belotero SOFT, Merz Aesthetics) using blunt-tip microcannula. ,Other side of upper lip was augmented with a total volum
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Lip augmentation with blunt-tip microcannula,Lip augmentation with sharp needle

Sponsors

Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Participants aged 18-60 years who desired to have a lip filler treatment

Exclusion criteria

Exclusion criteria: The criteria for exlusion were major underlying medical conditions, pregnancy, active skin disorders or recurrent herpes infection in the experimental region, a history of allergic response to HA fillers, or a history of lip augmentation with HA fillers within 12 months.

Design outcomes

Primary

MeasureTime frame
Efficacy Immediately after HA filler injection and 2 weeks after HA filler injection Change on the Merz scale for lip fullness, Naturalness, Change on the Global Aesthetic Improvement Scale (GAIS), Patient satisfaction

Secondary

MeasureTime frame
Pain score Immediately after HA filler injection 10-cm Visual Analogue Score ,Side effect Immediately after HA filler injection Monitor and self-reported

Countries

Thailand

Contacts

Public ContactVasanop Vachiramon

Faculty of Medicine, Ramathibodi hospital

vasanop@gmail.com0946369165

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026