Salivary Iron Level in Oral Lichen Planus Patients Undergoing Topical Corticosteroid Therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20220602006

Enrollment

102

Registered

2022-06-02

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

OLP patients undergoing topical corticosteroid therapy oral lichen planus, topical corticosteroid, salivary iron, oral candidiasis

Interventions

OLP patients, confirmed by clinical appearance and histopathologic report. History of oral candidiasis, confirmed by clinical appearance and laboratory report.,OLP patients, confirmed by clinical app

Diagnostic,Diagnostic,Diagnostic

OLP patients undergoing topical corticosteroid therapy with history of oral candidiasis,OLP patients undergoing topical corticosteroid therapy without history of oral candidiasis,Healthy volunteers

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy volunteers and OLP patients 2. OLP lesions with score 2, 3, 4 or 5 according to Thongprasom score 3. OLP lesions treated with 0.1%FAO for at least 1 month 4. OLP lesions with history of oral candidiasis reported from both clinical appearance and laboratory report 5. No oral candidiasis on saliva collected date 6. No other autoimmune disease or uncontrolled diabetes mellitus, hypothyroidism, hypoparathyroidism and hypoadrenocorticism or medical conditions predisposing to oral candidiasis 7. No hematologic diseases 8. No history of blood donation or major blood loss for 4 months before participate in the study 9. No severe periodontal disease 10. No wearing removable denture 11. No history of antifungal therapy for 2 weeks before participate in the study 12. No taking iron supplement for 2 months before participate in the study 13. No taking other systemic or local immunosuppressants 14. No smoking for 1 month before participate in the study 15. No menstruation on saliva collected date

Exclusion criteria

Exclusion criteria: 1. Hyposalivation 2. Withdraw from the study

Design outcomes

Primary

Measure	Time frame
salivary iron level 2 weeks after last subject ppm	—

Secondary

Measure	Time frame
colony count of Candida in saliva 1 week after each subject logCFU/ml	—

Countries

Thailand

Contacts

Public ContactChanwit Prapinjumrune

Faculty of Dentistry, Chulalongkorn University

chanwit.p@chula.ac.th022188942

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026