Transfusion dependent thalassemias Sarcopenia Osteopenia and osteoporosis Transfusion dependent thalassemias Sarcopenia Osteopenia and osteoporosis Dietary supplementation Resistance exercise Resistact
Conditions
Interventions
Volunteers ,who have diagnosed sarcopenia according to Criteria from Asian working group on sarcopenia 2019, will received dietary supplementation (Fresubin two-kcal fibre drink or Fresubin whey prote
Experimental Other
Dietary supplementation and Resistance exercise
Sponsors
The Thai Red Cross society
The endocrine society of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosed transfusion dependent thalassemia Diagnosed sarcopenia according to criteria of Asian working group on sarcopenia 2019 Age >= 18 years New York Heart Association (NYHA) functional class I
Exclusion criteria
Exclusion criteria: not willing to or unable to complete the project for the full 6 month period pregnancy co-morbidites with heart , lung , liver , kidney disease which is not suitable to receive dietary supplementation and resistance exercise program
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| muscle mass 6 months BMD ,muscle strength 6 months hand grip strength ,physical functions 6 months 6-meter walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life 6 months SarQol score | — |
Countries
Thailand
Contacts
Public ContactPhunnisa Talkijkul
Internal medicine department , Faculty of medicine Chulalongkorn university
Outcome results
None listed