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Efficacy and safety of Autologous Fibroblasts on Acne Scars

Efficacy and Safety of Autologous Fibroblasts on Acne Scars

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220528005
Enrollment
30
Registered
2022-05-28
Start date
2022-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with moderate to severe acne scars in cheek areas by global acne scar grading system Acne scars

Interventions

Each patient had their tissue collected at the post-auricular area. Preoperatively, 2 percent lidocaine was injected and 2 6-mm punch biopsy was performed. The donor site was closed with a nylon 5-0 s
Experimental Procedure/Surgery

Sponsors

Research department, Faculty of Medicine Siriraj Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with moderate to severe acne scars in cheek areas by global acne scar grading system

Exclusion criteria

Exclusion criteria: (1) were pregnant or lactating; (2) had a history of connective tissue disorder, skin cancers, or related diseases; (3) had previous autologous fibroblast treatment; (4) had previous treatment with fillers, lasers, or energy-based devices within the last 12 months; (5) had previous treatment using transdermal drug delivery, chemical peeling or topical retinoid within the last month; or (6) had an allergy to collagen, meat and dairy products, gentamycin, amphotericin B, or related products.

Design outcomes

Primary

MeasureTime frame
Acne scar depression 1-, 3-, 6-, and 12-months follow-up The decreasing of acne scars depression captured by Antera 3D imaging system

Secondary

MeasureTime frame
Skin roughness 1-, 3-, 6-, and 12-months follow-up The degree of skin roughness captured by Antera 3D imaging system,safety 1-, 3-, 6-, and 12-months follow-up history taking and physical examination

Countries

Thailand

Contacts

Public ContactRungsima Wanitphakdeedecha

Faculty of Medicine Siriraj Hospital, Mahidol University

rungsima.wan@mahidol.ac.th0816406300

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026