Hepatic encephalopathy Bacterial translocation, hepatic encephalopathy, cirrhosis, plasma 16s ribosomal bacterial DNA, psychometric hepatic encephalopathy score
Conditions
Interventions
Cirrhotic patients with hepatic encephalopathy was diagnosed by the West-Haven criteria or Psychometric hepatic encephalopathy score of 4 or greater.,Cirrhotic patients who did not meet the criteria o
Supportive Care,Supportive Care
Hepatic encephalopathy,No hepatic encephalopathy
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with cirrhosis diagnosed by radiological findings 2. Age 18-80 years
Exclusion criteria
Exclusion criteria: 1. Consumption of antibiotics, psychotropic drugs, or any antibiotics in the preceding two weeks 2. History of any bacterial infections during the past two weeks 3. Presence of active neurological or psychiatric diseases 4. Previous transjugular intrahepatic portosystemic shunt (TIPS) or shunt surgery 5. Alcohol misuse in the previous three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hepatic encephalopathy at begin of the study West Haven criteria or the Psychometric Hepatic Encephalopathy score of 4 or greater | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory markers at begin of the study IL-6, TNF-a, lipopolysaccharide-binding protein | — |
Countries
Thailand
Contacts
Public ContactKessarin Thanapirom
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital
Outcome results
None listed