visible topographic enlarged facial pores enlarged facial pores
Conditions
Interventions
Botulinum toxin A, 16 units in 1 ml of normal saline, was applied to the randomized treatment side of the participant'
s face, then the micro-needling was used. The depth of micro-needling was 1.5 mm and 1.75 mm for the upper and lower cheek, respectively. The overlap between shots was 10%, and the number of shots was
s cheeks size.,The normal saline solution of 1 ml was applied to the randomized treatment side of the participant'
s cheeks size.
Experimental Procedure/Surgery,Placebo Comparator Procedure/Surgery
Botulinum toxin,Control
Sponsors
Department of Dermatology, Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
25 Years to 50 Years
Inclusion criteria
Inclusion criteria: participants with visible topographic enlarged facial pores confirmed by a dermatologist
Exclusion criteria
Exclusion criteria: 1. photosensitive dermatoses, Skin malignancy, keloid, immunocompromised host, dermatitis or infection at the treatment area 2. regular smoking 3. Pregnancy and lactating woman first 3 months 4. Cannot come back for follow up 5. AHA, retinoic acid, or topical agents for acne scar within 6 months 6. Laser, RF within 3 months 7. Systemic steroid, immunosuppressive agents within 6 months 8. Oral isotretinoin within 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial pores size at 2 weeks, 1 months, 3 months and 6 months after intervention change in selected area of the facial pore size captured by Antera 3D imaging program | — |
Secondary
| Measure | Time frame |
|---|---|
| Sebum production at 2 weeks, 1 months, 3 months and 6 months after intervention Change in sebum production measured by Sebumeter,Safety at 2 weeks, 1 months, 3 months and 6 months after intervention history tajing and physical examination | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed