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Optimal mean airway pressure in high frequency oscillatory ventilation guided by electrical impedance tomography in children with acute respiratory distress syndrome

Optimal mean airway pressure in high frequency oscillatory ventilation guided by electrical impedance tomography in children with acute respiratory distress syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20220521002
Enrollment
10
Registered
2022-05-21
Start date
2020-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric patients admitted to PICU with moderate to severe ARDS using HFOV Pediatric, Acute respiratory distress syndrome, High frequency oscillatory ventilation, Electrical impedance tomography, Optimal mean airway pressure, Lung recruitment.

Interventions

To determine the optimal MAP in HFOV, we used the protocols of a previous study (ISRCTN 19924570) (Appendix A), which identified the optimal MAP in HFOV by decremental titration after lung recruitment
Treatment,Treatment
Optimal MAP in HFOV using the protocol,optimal MAP in HFOV obtained from EIT

Sponsors

The study received no financial support.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Months to 15 Years

Inclusion criteria

Inclusion criteria: Pediatric patients with moderate to severe ARDS (oxygen index (OI) more than 12) according to the Pediatric Acute Lung Injury Consensus Conference (PALICC) definition using HFOV

Exclusion criteria

Exclusion criteria: cyanotic heart disease, severe obstructive airway disease, unstable spines or did not consent.

Design outcomes

Primary

MeasureTime frame
Optimal MAP in HFOV After procedure Analyzed the optimal MAP from the protocols together with EIT

Secondary

MeasureTime frame
Effect of lungs recruitment maneuvers After procedure Hemodynamics, ABG and lung volume observed from CXR

Countries

Thailand

Contacts

Public ContactRujipat Samransamruajkit

Division of Pediatric Pulmonology and Critical Care Department of Pediatrics, King Chulalongkorn Memorial Hospital

Rujipatrs@gmail.com022565278

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026