Dynamic arterial elastance for predicting mean arterial pressure responsiveness after fluid challenge in spontaneously breathing septic patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20220517001

Enrollment

Registered

2022-05-17

Start date

2022-05-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneously breathing septic patient with Acute circulatory failure who is predicted fluid response by mini-fluid challenge test dynamic arterial elastance spontaneous breathing sepsis acute circulatory failure fluid responsiveness

Interventions

Spontaneously breathing septic patients that predicted fluid response

Diagnostic

Fluid responsiveness group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Spontaneously breathing septic patient 2. Acute circulatory failure 3. Fluid responsiveness (mini-fluid challenge using colloid 100mL or passive leg raising test : increase SV or CO greater than or equal to 10% )

Exclusion criteria

Exclusion criteria: 1. Cardiac arrhythmia 2. Right heart failure 3. Using inotropic drug 4. Intraabdominal pressure > 12 mmHg 5. Heart rate to Respiratory rate ratio less than 3.6 6. Deny participation

Design outcomes

Primary

Measure	Time frame
sensitivity and specificity of Eadyn before fluid loading FloTrac connected to Hemosphere Monitoring	—

Secondary

Measure	Time frame
Cut-point value of Eadyn before fluid loading FloTrac connected to Hemosphere Monitoring	—

Countries

Thailand

Contacts

Public ContactSubundit Injampa

Faculty of Medicine Ramathibodi Hospital, Mahidol University

subundit.inj@mahidol.edu66022011513

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026