Healthy human volunteers PRP, Platelet-rich plasma, Melasma
Conditions
Interventions
50 ml of blood was drawn from volunteer and the blood was centrifuged to get PRP by using Smartprep machine. The PRP was injected into melasma lesion. This process was repeated for 2 more times every
Experimental Device
PRP for melasma
Sponsors
Dermatologic Surgery, Dermatology department, Siriraj hospital, Thailand
Terumo Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Epidermal or mixed types melasma2. Thais 3. Healthy
Exclusion criteria
Exclusion criteria: 1. pregnant or lactating woman 2. Having severe acnes 3. Having the skin disease around the treated area 4. Using an energy-based device or other interventions around treated area 6 months prior
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma improvement Every treatment visits, 14 days, 1, 2, 3, and 6 months after the intervention Level of improvement measure from Antera3d,Subject self assessment score Every treatment visits, 14 days, 1, 2, 3, and 6 months after the intervention percentage of Subject self assessment score,Physicians assessment score Every treatment visits, 14 days, 1, 2, 3, and 6 months after the intervention percentage of Physicians assessment score | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score immediate after the intervention Visual analogue scale (0-10),Adverse reaction Every treatment visits, 14 days, 1, 2, 3, and 6 months after the intervention Descriptive report | — |
Countries
Thailand
Contacts
Public ContactSurachet Sirisuthivoranunt
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed